Electrochemical paper-based antigen sensing platform using plant-derived monoclonal antibody for detecting SARS-CoV-2Article Published on 2023-01-012022-11-15 Journal: Talanta [Category] SARS, 진단, 치료기술, 치료제, [키워드] anti-SARS-CoV-2 antibody Antigen applicability applied approach Cellulose Concentration COVID-19 diagnosis CR3022 detect diagnostic Differential pulse voltammetry expressed functional group limit of detection linear relationship monoclonal antibody nasopharyngeal swab sample Nicotiana benthamiana Paper-based electrochemical immunosensor Plant-based antibody platform point-of-care pulse quantification RBD Receptor binding domain Saliva SAR-CoV-2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2. Spike protein the RBD this system was performed [DOI] 10.1016/j.talanta.2022.123783 PMC 바로가기
Could red cell distribution width be used for predicting cardiac injury in neonates with COVID-19?Article Published on 2022-12-012022-11-15 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 바이오마커, [키워드] Affect all age group calculated coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 pandemic COVID-19 cut-off value determine Diagnosis died Diseases distribution Fever group Hospitalization illness immature immunologically Inflammation Inflammatory Injury Laboratory life-threatening management nasopharyngeal swab sample Neonatal Neonate Neonates Newborn Patient PCR PCR-positive polymerase chain populations positive Prognosis prognostic prognostic biomarker Prognostic value Red cell Red cell distribution width SARS-CoV-2 SARS-COV-2 infection screened Sensitivity and specificity severe disease significantly higher syndrome systemic inflammatory the patient troponin level troponin levels troponin. were used [DOI] 10.1002/jmv.28050 PMC 바로가기
Discriminative electrochemical biosensing of wildtype and omicron variant of SARS-CoV-2 nucleocapsid protein with single platformArticle Published on 2022-11-152022-11-15 Journal: Analytical biochemistry [Category] SARS, 변종, 진단, 치료기술, [키워드] antibody Antigen COVID-19 detect Electrochemical biosensing platforms evaluated linear Microscopy nasopharyngeal swab sample nucleocapsid antigen Nucleocapsid antigen protein omicron Omicron variant platform produced Protein SARS-CoV-2 SARS-CoV-2 nucleocapsid the SARS-CoV-2 Voltammetry. wildtype X-ray X-ray spectroscopy [DOI] 10.1016/j.ab.2022.114898 PMC 바로가기
Differential Infectivity of Original and Delta Variants of SARS-CoV-2 in Children Compared to AdultsArticle Published on 2022-10-262022-11-16 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] acute respiratory syndrome Adults age aliquot B.1.617.2 Canada characteristic children circulating circulating SARS-CoV-2 variants coronavirus COVID-19 Culture cycle threshold Delta delta variant demographics determine dose driver implicated in viral Infection infectious titers infective Infectivity mechanism Mutation Nasopharyngeal swab nasopharyngeal swab sample original pediatric positive predominant provided RT-PCR SARS-CoV-2 SARS-CoV-2 RT-PCR screened statistical analysis susceptible TCID TCID50 TCID50. tissue Transmission variant variants of concern variety Viral RNA VoC [DOI] 10.1128/spectrum.00395-22 PMC 바로가기
Sensitivity analysis of rapid antigen tests for the Omicron SARS-CoV-2 variant detection from nasopharyngeal swab samples collected in Santiago of ChileArticle Published on 2022-10-202022-11-15 Journal: Frontiers in Public Health [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] Analysis Antigen circulation collected Contagion contagiousness COVID-19 COVID-19 pandemic decrease Detection sensitivity evaluate faster genomic greater Health authority highlight immune evasion increasingly indicate Infection limit Local Mutation nasopharyngeal swab sample NPSs omicron Omicron detection outbreak pandemic pandemic in Chile Patient predominant Prevent rapid antigen test rapid antigen test. RAT RATs reduce RT-PCR RT-qPCR SARS-CoV-2 SARS-CoV-2 variant sensitivity suggested tested the SARS-CoV-2 virus variant viral amplification Viral load viral loads Viral variants VoC [DOI] 10.3389/fpubh.2022.976875 PMC 바로가기
Epigenetic mechanisms and host factors impact ACE2 gene expression: Implications in COVID-19 susceptibilityResearch article Published on 2022-10-012022-10-05 Journal: Infection, genetics and evolution : journal of mol [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] ACE2 gene ACE2 protein age angiotensin-converting enzyme 2 Arterial hypertension association Asthma BMI body mass index changes in clinical variable clinical variables COVID-19 COVID-19 susceptibility described determinant disease susceptibility DNA methylation Epigenetic epigenetics evaluate evaluated expression expression profile Factor Host host cell host factors Infection involved Male sex mechanism Methylation molecular cause mRNA expression nasopharyngeal swab sample obesity overexpression Peripheral blood promoter region quantified regulated Result risk factor RT-qPCR SARS-CoV-2 SARS-COV-2 infection Sex significant difference smoking study group susceptibility the disease type II diabete underlying disease Variability variable virus volunteers was determined [DOI] 10.1016/j.meegid.2022.105357 [Article Type] Research article
Saliva sample for detection of SARS-CoV-2: A possible alternative for mass testingArticle Published on 2022-09-282022-11-15 Journal: PLoS ONE [Category] SARS, 치료기술, [키워드] Accuracy Analysis analyzed comparable COVID-19 COVID-19 diagnosis COVID-19 pandemic COVID-19 testing Critical demographic diagnostic disease drooling E gene effective Effectiveness female individual male moderate nasal swabs Nasopharyngeal swab nasopharyngeal swab sample Negative predictive value Nigeria outbreak pandemic participant Participants plethora polymerase chain positive presenting provide reducing risk RT-PCR RT-PCR test Saliva saliva sample SARS-CoV-2 SARS-CoV-2 RdRp sensitivity significantly Specificities specimen Swab [DOI] 10.1371/journal.pone.0275201 PMC 바로가기
Comparative Performance of the Luminex NxTAG Respiratory Pathogen Panel, GenMark eSensor Respiratory Viral Panel, and BioFire FilmArray Respiratory PanelArticle Published on 2022-08-312022-11-15 Journal: Microbiology Spectrum [Category] 진단, [키워드] Accuracy Adenovirus assays BioFire Characteristics clinical laboratory collected Comparative coronavirus COVID-19 diagnostic disease Endemic false-positive result GenMark in vitro Increased influenza A influenza B Luminex Luminex assay métapneumovirus nasopharyngeal swab sample no significant difference Panel parainfluenza performance positive respiratory respiratory pathogen respiratory pathogen panels respiratory syncytial virus respiratory viral respiratory viral panels significant difference symptomatic patient Syndromic testing. The United States viruses [DOI] 10.1128/spectrum.01248-22 PMC 바로가기
A fast and sensitive absolute quantification assay for the detection of SARS-CoV-2 peptides using parallel reaction monitoring mass spectrometry병렬 반응 모니터링 질량 분석을 사용한 SARS-CoV-2 펩타이드 검출을 위한 빠르고 민감한 절대 정량 분석Article Published on 2022-08-152022-09-11 Journal: Journal of proteomics [Category] COVID19(2023년), SARS, 치료기술, 치료법, 치료제, [키워드] Absolute quantification Clinical diagnosis clinics COVID-19 Ct values Early detection enrichment heat heat-inactivated high resolution high viral load investigated mass mass spectrometry Nasopharyngeal swab nasopharyngeal swab sample Orbitrap pandemic Patient peptide peptides positive positive patient positive patients PRM Protein quantification required RT-qPCR SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 nucleocapsid SARS-CoV-2 peptide SARS-CoV-2. sensitivity speed Surveillance swab samples the disease Viral load Viral protein Viral proteins [DOI] 10.1016/j.jprot.2022.104664 PMC 바로가기 [Article Type] Article
Effectiveness of third vaccine dose for coronavirus disease 2019 during the Omicron variant pandemic: a prospective observational study in Japan오미크론 변종 대유행 중 코로나바이러스 질병 2019에 대한 3차 백신 접종의 효과: 일본의 전향적 관찰 연구Observational Study Published on 2022-08-102022-09-11 Journal: Scientific Reports [Category] SARS, 변종, 임상, [키워드] 95% confidence interval administration booster dose caused Chain Reaction close contact contact with coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 cases COVID-19 vaccine dose doses Effectiveness enrolled evaluated highest Infection Japan mass vaccination mRNA Nasopharyngeal swab nasopharyngeal swab sample Nasopharyngeal swab samples occurred omicron Omicron variant outbreak participant Participants polymerase chain reaction Prevent progressed progression prospective observational study receiving Ribonucleic acid RT-PCR RT-PCR test Swab test tested vaccination Vaccine vaccine dose variant were excluded with COVID-19 [DOI] 10.1038/s41598-022-17990-7 PMC 바로가기 [Article Type] Observational Study